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Pneumococcal
 
Pneumococcal disease is an infection caused by a bacteria. When these bacteria invade the lungs, they cause the most common type of pneumococcal disease, pneumococcal pneumonia. The same bacteria can also attack the bloodstream (bacteremia) and/or the brain (meningitis). Pneumococcal pneumonia alone infects about 500,000 people in the United States every year. Every year, about 40,000 people die of pneumococcal infections. The most common symptoms of pneumococcal pneumonia are sudden shaking, chills, cough, and fever.

Pneumococcal disease is a bacterial infection, so it is treated with antibiotics. However, many strains are becoming resistant to the antibiotics usually used. When someone is infected with an antibiotic-resistant strain, only very expensive antibiotics, often with much higher risks of side effects, can be used.

Because pneumococcal infection is common in infants and children under 2 years of age, a new vaccine, pneumococcal conjugate 7 valent vaccine (PCV), is recommended for all children 2-23 months of age and for some children 24-59 months.

Some people are at high risk for pneumococcal disease - the following persons should be vaccinated with pneumococcal polysaccharide (23-valent) vaccine:
  • Persons age 65 years and older
  • Persons with chronic heart, lung, or liver disease
  • Persons with diabetes
  • Persons with immunologic disorders or who are immunocompromised (cancer patients, persons with HIV infection, organ transplants, and those receiving steroids, chemotherapy, or radiation therapy)
  • Persons who have had their spleen removed or have dysfunction of the spleen due to sickle cell anemia
  • Persons who have a leakage of spinal fluid, or nephrotic syndrome (a chronic kidney condition that causes loss of protein through the urine)
  • Persons with organ or bone marrow transplants
  • Persons with chronic kidney failure
Older adults who received their first dose before age 65 should receive a second dose after 65 if 5 years have passed since the first dose. Some individuals should receive a second dose of pneumococcal vaccine if 5 or more years have elapsed (3 or more years in the case of persons age 10 years or less) since their first dose of vaccine:
  • Persons with organ or bone marrow transplants
  • Persons who have had their spleen removed, or whose spleen is damaged (such as from sickle cell anemia)
  • Persons who were less than age 65 years at the time of their first dose of vaccine
  • Persons with immunologic disorders or who are immunocompromised (cancer patients, persons with HIV infection, organ transplants, and those receiving steroids, chemotherapy, or radiation therapy)
Other than these exceptions, there is currently no routine indication for a second dose of pneumococcal vaccine.

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