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Infectious Disease Epidemiology

Methicillin-resistant Staphylococcus aureus (MRSA)

Lab Criteria for Diagnosis (invasive disease)

  • Isolation of Staphylococcus aureus from a normally sterile site. Examples of sterile sites include, but are not limited to: cerebral spinal fluid, blood, peritoneal fluid, or pleural fluid.

AND

  • Intermediate or high level resistance of the Staphylococcus aureus isolate to methicillin, detected and defined according to the standards and guidelines approved by the National Committees for Clinical Laboratory Standards (NCCLS) (MIC: 4-8 mg/L for intermediate and >16 mg/L for high (NCCLS 2006)).

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